zinc(II) chloride in dichloromethane Ambient temperature;

1.1: zinc dibromide / dichloromethane / 1.5 h / 20 - 45 °C / Industry scale 2.1: sodium hydroxide; water / methanol / 16 h / 70 °C / Industry scale 2.2: 10 °C / pH ~ 1.5 / Industry scale 3.1: Oxonereg; / dichloromethane / 24 h / 15 °C / Industry scale 4.1: triethylamine; diphenyl phosphoryl azide / toluene / 9 h / 80 °C / 760.05 Torr / Industry scale; Reflux 5.1: triethylamine / toluene; water / 7 h / 0 - 20 °C / Industry scale 6.1: benzotriazol-1-ol; 4-methyl-morpholine; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide / acetonitrile; water / 5 h / 5 - 40 °C / Industry scale 7.1: sodium hydroxide; water / 2-methyl tetrahydrofuran / 7 h / 20 - 60 °C / Industry scale 7.2: 0.17 h / 20 - 30 °C / pH 1.5 - 3 / Industry scale 8.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide / ethyl acetate; acetonitrile; water / -5 - 30 °C / Industry scale 9.1: sodium acetate; sodium hypochlorite; acetic acid; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / methyl acetate; water; tert-butyl methyl ether / 2 h / 5 - 15 °C / Industry scale View Scheme

titanium(IV) isopropylate; titanium tetrachloride 1.) CH2Cl2, -78 deg C, 1 h, 0 deg C, 2 h; 2.) H2O, DME, heating, 3 h; Yield given. Multistep reaction. Yields of byproduct given;

1: 1.) Ti(i-PrO)4, TiCl4 / 1.) CH2Cl2, -78 deg C, 1 h, 0 deg C, 2 h; 2.) H2O, DME, reflux, 3 h 2: 52 percent / triphenylmethanol, potassium / xylene / 1 h / Heating View Scheme

water; zinc(II) chloride in dichloromethane T=20 - 25°C; Yield given. Yields of byproduct given;

methanol; copper diacetate; trimethylsilyl trifluoromethanesulfonate 1.) MeCN, 25-30 deg C, 8 h, 2.) heating, 0.5 h; Yield given. Multistep reaction;

trichlorophosphate 1.) CH2Cl2, 0-10 deg C, 30 min; 2.) room temp., 15 h; Yield given. Multistep reaction;

1: 85 percent / Me3SiOSO2CF3 / CH2Cl2 / Ambient temperature 2: MeOH / Heating View Scheme

titanium tetrachloride

1: With titanium tetrachloride in dichloromethane T=-60 - -20°C; 2: With toluene-4-sulfonic acid in dichloromethane T=20°C;