1: 1-trifluoromethyl-4-bromobenzene With (nBu)3MgLi in tetrahydrofuran
T=0°C; 0.0833333 h;
2: bromobenzene With Cl2Ni(1,2-bis(diphenylphosphino)ethane) in tetrahydrofuran
T=0°C; Kumada-Corriu cross-coupling; Further stages. Title compound not separated from byproducts.;
参考文献
Lau, Stephen Y. W.; Hughes, Greg; O'Shea, Paul D.; Davies, Ian W.
Organic Letters, 2007 , vol. 9, # 11 p. 2239 - 2242
palladium diacetate in tetrahydrofuran
T=50°C; Kumada coupling; 16 h;
参考文献
Alimardanov, Asaf; Schmieder-Van De Vondervoort, Lizette; De Vries, Andre H. M.; De Vries, Johannes G.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1812 - 1817
palladium diacetate in N,N-dimethyl-formamide
T=50°C; Negishi coupling; 16 h; Title compound not separated from byproducts;
参考文献
Alimardanov, Asaf; Schmieder-Van De Vondervoort, Lizette; De Vries, Andre H. M.; De Vries, Johannes G.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1812 - 1817
