1-(4-硝基苯基)丁烷-1,3-二酮合成路线 （共 22 条）
反应条件
in tetrahydrofuran; hexane
T=-78°C; 0.0833333 h;
参考文献
Andrews, Philip C.; Gee, William J.; Junk, Peter C.; Krautscheid, Harald
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 3 p. 698 - 705
反应条件
sulfuric acid in water
Heating;
参考文献
Regitz,M.
Chemische Berichte, 1966 , vol. 99, p. 3128 - 3147
反应条件
1: L-proline / dimethyl sulfoxide / 5 h / 20 °C / |Inert atmosphere
2: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / acetonitrile / 2 h / 0 °C / |Inert atmosphere; |Reflux
View Scheme
参考文献
Bel Abed, Hassen; Mammoliti, Oscar; Bande, Omprakash; Van Lommen, Guy; Herdewijn, Piet
Journal of Organic Chemistry, 2013 , vol. 78, # 16 p. 7845 - 7858
反应条件
1.1: dichloro(cycloocta-1,5-diene)palladium(II); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; magnesium chloride; triethylamine / 1,4-dioxane / 80 °C / |Glovebox; |Inert atmosphere
1.2: 80 °C / |Glovebox; |Inert atmosphere
1.3: 18 h / 80 °C
2.1: hydrogenchloride / water / 1 h / 80 °C
View Scheme
参考文献
Korsager, Signe; Nielsen, Dennis U.; Taaning, Rolf H.; Lindhardt, Anders T.; Skrydstrup, Troels
Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 17687 - 17691
反应条件
diethyl ether; sodium amide
T=-17°C;
参考文献
Burgess
Journal of the Chemical Society, 1927 , p. 2017
反应条件
in dimethyl sulfoxide
T=20°C; 1 h;
参考文献
Isart, Carles; Bures, Jordi; Vilarrasa, Jaume
Tetrahedron Letters, 2008 , vol. 49, # 37 p. 5414 - 5418
反应条件
in dimethyl sulfoxide
T=20°C; 30 h;
参考文献
Isart, Carles; Bures, Jordi; Vilarrasa, Jaume
Tetrahedron Letters, 2008 , vol. 49, # 37 p. 5414 - 5418
反应条件
aluminium trichloride; tetrachloroethane, 1,1,2,2-
参考文献
Sieglitz; Horn
Chemische Berichte, 1951 , vol. 84, p. 607,615
反应条件
sodium hydroxide; calcium chloride; benzene
参考文献
Sabnis et al.
Journal of Scientific and Industrial Research, 1958 , vol. 17 A, p. 421,422
反应条件
sodium hydride
1.) DMF, mineral oil, 2.) DMF, mineral oil, heating; Yield givenMultistep reaction;
参考文献
Karnik, A. V.; Rane, J. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1998 , vol. 37, # 11 p. 1191 - 1193
