4,6-二苯基-2-氨基嘧啶合成路线 (共 28 条)
反应条件
potassium methanolate in ethanol
T=70°C; 20.67 h; Heating / reflux;
参考文献
Ciba Specialty Chemicals Corporation
Patent: US6706215 B1, 2004 ;
Location in patent: Page column 40 ;
反应条件
sodium hydroxide in water
0.0166667 h; Microwave irradiation;
参考文献
Thanh, Nguyen Dinh; Mai, Nguyen Thi Thanh
Carbohydrate Research, 2009 , vol. 344, # 17 p. 2399 - 2405
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water
T=110°C; Suzuki-Miyaura cross-coupling; 12 h;
参考文献
Yaziji, Vicente; Rodriguez, David; Gutierrez-De-Teran, Hugo; Coelho, Alberto; Caamano, Olga; Garcia-Mera, Xerardo; Brea, Jose; Loza, Maria Isabel; Cadavid, Maria Isabel; Sotelo, Eddy
Journal of Medicinal Chemistry, 2011 , vol. 54, # 2 p. 457 - 471
反应条件
sodium hydroxide in ethanol
10 h; Reflux;
参考文献
Kanagarajan; Thanusu; Gopalakrishnan
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 4 p. 1583 - 1589
反应条件
sodium in isopropyl alcohol
8 h; Reflux;
参考文献
Roouf Bhat, Abdul; Arshad, Mohammad; Ju Lee, Eun; Pokharel, Smritee; Choi, Inho; Athar, Fareeda
Chemistry and Biodiversity, 2013 , vol. 10, # 12 p. 2267 - 2277
反应条件
sodium carbonate in ethanol
10 h; Heating;
参考文献
Dora; Dash; Panda
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 691 - 696
反应条件
in ethanol
T=78°C; 8 h;
参考文献
Rawal, Ravindra K.; Tripathi, Rajkamal; Katti; Pannecouque, Christophe; De Clercq, Erik
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 9 p. 3134 - 3142
反应条件
sodium ethanolate in ethanol
4 h; Heating;
参考文献
Glotova; Dvorko; Albanov; Protsuk
Russian Journal of Organic Chemistry, 2007 , vol. 43, # 1 p. 121 - 125
反应条件
1: With silica gel in dichloromethane
2: 0.0833333 h; Microwave irradiationNeat (no solvent);
参考文献
Chen, Qing-Zhen; Ding, Zong-Cang; Ma, Yan-Li; Wang, Zhen-Dong; Zhan, Zhuang-Ping
Heterocycles, 2012 , vol. 85, # 8 p. 1891 - 1896
反应条件
potassium carbonate
0.166667 h; microwave irradiation;
参考文献
Goswami, Shyamaprosad; Jana, Subrata; Dey, Swapan; Kumar Adak, Avijit
Australian Journal of Chemistry, 2007 , vol. 60, # 2 p. 120 - 123