4-硝基-α-甲苯磺酰氯合成路线 （共 21 条）
参考文献
Sprague; Johnson
Journal of the American Chemical Society, 1937 , vol. 59, p. 1837,1839
参考文献
Baganz; Kessler
Chemische Berichte, 1955 , vol. 88, p. 1995
反应条件
1: chloroform / 4 h / 20 °C 2: hydrogen / palladium 10 on activated carbon / methanol / 4 h View Scheme
参考文献
WO2011/46970 A1, ;
WO 2011/046970 A1
反应条件
in chloroform T=20°C; 4 h;
参考文献
MYREXIS, INC.; HOLCOMB, Ryan; SUZUKI, Kazuyuki; HALTER, Robert J.; SEBAHAR, Paul R.; MCLEOD, Donald A.; SHENDEROVICH, Mark D.; YAGER, Kraig M.; BURSAVICH, Matthew Gregory; YUNGAI, Ashantai J.; RICHARDS, Burt; BARTEL, Paul L.; WETTSTEIN, Daniel A.
Patent: WO2011/46970 A1, 2011 ;
Location in patent: Page/Page column 125 ;
WO 2011/046970 A1
反应条件
methylamine in dichloromethane
参考文献
Merck Sharp and Dohme Ltd.
Patent: US5854247 A1, 1998 ;
反应条件
in chloroform; benzene
参考文献
Orazi; Corral; Bravo
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 6 p. 1701 - 1708
反应条件
dichlorotris(triphenylphosphine)ruthenium(II) T=80°C; 72 h;
参考文献
Phosphorus and Sulfur and the Related Elements, , vol. 20, p. 139 - 144
反应条件
T=125°C; Pyrolysis; Rate constant;
参考文献
Rieche; Naumann
Journal fuer Praktische Chemie (Leipzig), 1959 , vol. <4>9, p. 108,112,113
反应条件
triethylamine in ethyl acetate
T=0°C;
参考文献
Shealy, Y. Fulmer; Krauth, Charles A.; Struck, Robert F.; Montgomery, John A.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 8 p. 1168 - 1173
反应条件
ammonia; (NH4)2CO3 in water; acetonitrile
T=20°C; 1 h; Product distribution / selectivity;
参考文献
Schauerte, Heike; Allgeier, Hans; Pleiss, Michael A.; Augustin, Martin; Peraus, Gisela; Stumm, Gabriele; Wabnitz, Philipp
Patent: US2010/184780 A1, 2010 ;
Location in patent: Page/Page column 21-22; 23; 24 ;
