2-(4-氨基苯基)-N-[(4-甲基苯基)磺酰基]乙酰胺合成路线 （共 3 条）
反应条件
tin(ll) chloride in ethanol; N,N-dimethyl-formamide
T=70°C; 1 h;
参考文献
Uehling, David E.; Donaldson, Kelly H.; Deaton, David N.; Hyman, Clifton E.; Sugg, Elizabeth E.; Barrett, David G.; Hughes, Robert G.; Reitter, Barbara; Adkison, Kim K.; Lancaster, Mary E.; Lee, Frank; Hart, Robert; Paulik, Mark A.; Sherman, Bryan W.; True, Timothy; Cowan, Conrad
Journal of Medicinal Chemistry, 2002 , vol. 45, # 3 p. 567 - 583
反应条件
1.1: CDI / CH2Cl2 / 1 h
1.2: CH2Cl2 / 1 h
1.3: 94 percent / DBU / CH2Cl2 / 16 h
2.1: 26 percent / tin(II) chloride hydrate / ethanol; dimethylformamide / 1 h / 70 °C
View Scheme
参考文献
Uehling, David E.; Donaldson, Kelly H.; Deaton, David N.; Hyman, Clifton E.; Sugg, Elizabeth E.; Barrett, David G.; Hughes, Robert G.; Reitter, Barbara; Adkison, Kim K.; Lancaster, Mary E.; Lee, Frank; Hart, Robert; Paulik, Mark A.; Sherman, Bryan W.; True, Timothy; Cowan, Conrad
Journal of Medicinal Chemistry, 2002 , vol. 45, # 3 p. 567 - 583
反应条件
1.1: CDI / CH2Cl2 / 1 h
1.2: CH2Cl2 / 1 h
1.3: 94 percent / DBU / CH2Cl2 / 16 h
2.1: 26 percent / tin(II) chloride hydrate / ethanol; dimethylformamide / 1 h / 70 °C
View Scheme
参考文献
Uehling, David E.; Donaldson, Kelly H.; Deaton, David N.; Hyman, Clifton E.; Sugg, Elizabeth E.; Barrett, David G.; Hughes, Robert G.; Reitter, Barbara; Adkison, Kim K.; Lancaster, Mary E.; Lee, Frank; Hart, Robert; Paulik, Mark A.; Sherman, Bryan W.; True, Timothy; Cowan, Conrad
Journal of Medicinal Chemistry, 2002 , vol. 45, # 3 p. 567 - 583
