3-甲基吡唑-5-甲酸乙酯合成路线 （共 40 条）
反应条件
diisobutylaluminium hydride in toluene T=-78°C;
参考文献
EP1757590 A1, ;
Page/Page column 5 ;
反应条件
1: N-bromosuccinmide / chloroform / 12 h / 20 °C 2: potassium carbonate / acetone / 10 h / 50 °C View Scheme
参考文献
Zhang, Da Qiang; Xu, Gao Fei; Fan, Zhi Jin; Wang, Dao Quan; Yang, Xin Ling; Yuan, De Kai
Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 669 - 672
反应条件
1: With water; sodium hydroxide in methanol 4 h; Reflux; 2: in methanol pH=2; Acidic conditions;
参考文献
Chinese Chemical Letters, , vol. 23, # 6 p. 669 - 672
反应条件
1.1: N-bromosuccinmide / chloroform / 12 h / 20 °C 2.1: potassium carbonate / acetone / 10 h / 50 °C 3.1: water; sodium hydroxide / methanol / 4 h / Reflux 3.2: pH 2 / Acidic conditions View Scheme
参考文献
Zhang, Da Qiang; Xu, Gao Fei; Fan, Zhi Jin; Wang, Dao Quan; Yang, Xin Ling; Yuan, De Kai
Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 669 - 672
参考文献
v. Auwers; Hollmann
Chemische Berichte, 1926 , vol. 59, p. 606,1296
反应条件
methanol; sodium methylate
参考文献
Dal Monte et al.
Gazzetta Chimica Italiana, 1956 , vol. 86, p. 797,808
参考文献
Chemische Berichte, , vol. 61, p. 2406,2410
Journal fuer Praktische Chemie (Leipzig), , vol. <2>126, p. 150,164
参考文献
Chemische Berichte, , vol. 61, p. 2406,2410
Journal fuer Praktische Chemie (Leipzig), , vol. <2>126, p. 150,164
反应条件
sodium hydroxide; (C4H9)4NBr phase transfer catalysis in water; benzene 4 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tarrago, Georges; Ramdani, Abdelkrim; Elguero, Jose; Espada, Modesta
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 137 - 142
反应条件
potassium iodide in N,N-dimethyl-formamide T=100°C; 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tarrago, Georges; Ramdani, Abdelkrim; Elguero, Jose; Espada, Modesta
Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 137 - 142
