1: 3-fluoropyridine With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-75 - -10°C; 0.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexane T=-70°C; 1 h; 3: With water in tetrahydrofuran; hexane T=0°C;
参考文献
MERCK and CO., INC.
Patent: WO2006/69287 A1, 2006 ;
Location in patent: Page/Page column 25; 26-27 ;
1: With sodium tetrahydroborate in tetrahydrofuran; hexane; water T=0°C; 0.0833333 h; 2: With hydrogenchloride in tetrahydrofuran; hexane; water T=0 - 40°C; 2 h; 3: With sodium hydroxide in tetrahydrofuran; hexane; water T=0 - 15°C; pH=12;
