2,4,6-三甲基苯甲醚合成路线 （共 13 条）
反应条件
sodium hydride in tetrahydrofuran
T=0 - 20°C; Methylation; 13 h;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
potassium hydroxide in water
T=60°C; Etherification; 2 h;
参考文献
Rettig, Martin; Sigrist, Andreas; Retey, Janos
Helvetica Chimica Acta, 2000 , vol. 83, # 9 p. 2246 - 2265
参考文献
Labaudiniere, L.; Burgada, R.
Tetrahedron, 1986 , vol. 42, # 13 p. 3521 - 3536
反应条件
1: 2,4,6-trimethyl-phenol With sodium hydride in tetrahydrofuran
T=5°C; Inert atmosphere;
2: sulfuric acid monomethylester in tetrahydrofuran
T=20°C; 1 h; Inert atmosphere;
参考文献
Casarini, Daniele; Mancinelli, Michele; Mazzanti, Andrea; Boschi, Francesca
Chirality, 2011 , vol. 23, # 9 p. 768 - 778
反应条件
tetra-(n-butyl)ammonium iodide
T=93°C; 19 h;
参考文献
Moss, Robert A.; Wang, Lei; Odorisio, Christina M.; Krogh-Jespersen, Karsten
Tetrahedron Letters, 2010 , vol. 51, # 11 p. 1467 - 1470
参考文献
Miller,B.
Journal of Organic Chemistry, 1977 , vol. 42, # 8 p. 1402 - 1408
反应条件
poly[(p-cyclopentadienylmethylstyrene)Rh(MeOH)n](CF3SO3)2
T=120°C; Substitution; 15 h;
参考文献
Goryunov; Steingarts
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 2 p. 246 - 251
反应条件
in dichloromethane; acetonitrile
-45 deg C to room temperature;
参考文献
Kol, Moshe; Rozen, Shlomo
Journal of Organic Chemistry, 1993 , vol. 58, # 6 p. 1593 - 1595
参考文献
Biedermann; Ledoux
Chemische Berichte, 1875 , vol. 8, p. 58
反应条件
sodium methylate
T=25 - 30°C; 2 h; carbon-paste anode (63 mA/cm2), stainless steel cathode;
参考文献
Barba, Isidoro; Chinchilla, Rafael; Gomez, Cecilia
Journal of Organic Chemistry, 1991 , vol. 56, # 11 p. 3673 - 3676
