(2E)-3-(4,5-二羟基-2-硝基苯基)丙烯酸合成路线 (共 5 条)
反应条件
boron tribromide in dichloromethane
12 h; Heating;
参考文献
Grenier, Jean-Luc; Cotelle, Nicole; Cotelle, Philippe; Catteau, Jean-Pierre
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 4 p. 431 - 434
反应条件
TNM; sodium carbonate in methanol; ethyl acetate
参考文献
Napolitano, Alessandra; D'Ischia, Marco
Journal of Organic Chemistry, 2002 , vol. 67, # 3 p. 803 - 810
反应条件
1: BBr3 / CH2Cl2 / 20 °C
2: CH2Cl2; H2O / 1 h / Heating
View Scheme
参考文献
Grenier; Cotelle; Catteau
Journal of Physical Organic Chemistry, 2000 , vol. 13, # 9 p. 511 - 517
反应条件
1: 11 percent / acidic nitrite / pH 2
2: Acid hydrolysis
View Scheme
参考文献
Cotelle, Philippe; Vezin, Herve
Tetrahedron Letters, 2001 , vol. 42, # 19 p. 3303 - 3305
参考文献
Cotelle, Philippe; Vezin, Herve
Tetrahedron Letters, 2001 , vol. 42, # 19 p. 3303 - 3305