(1S,3aR,6aS)-(2S)-2-环己基-N-(2-吡嗪基羰基)甘氨酰-3-甲基-L-缬氨酰八氢环戊并[c]吡咯-1-羧酸合成路线 （共 12 条）
反应条件
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 6 h / 20 °C / |Cooling with ice 2: sodium hydrogencarbonate; potassium bromide; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; sodium hypochlorite / dichloromethane / 20 h / 20 °C / |Cooling with ice View Scheme
反应条件
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide 2: water; trifluoroacetic acid / acetone / 22 h View Scheme
