反应条件
1: 1.) N-methylmorpholine, isobutyl chloroformate / 1.) DMF, -20 deg C, 5 min, 2.) 2 h
2: 92 percent / NH3 / methanol / 48 h / Ambient temperature
3: 93 percent / HCl, thioanisole / ethyl acetate / 0.5 h / Ambient temperature
View Scheme
参考文献
Chorev; Yaion; Wormser; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 2 p. 96 - 102
