3-氯-4-氟苯甲酸合成路线

Nelson, Derek W.; Gregg, Robert J.; Kort, Michael E.; Perez-Medrano, Arturo; Voight, Eric A.; Wang, Ying; Grayson, George; Namovic, Marian T.; Donnelly-Roberts, Diana L.; Niforatos, Wende; Honore, Prisca; Jarvis, Michael F.; Faltynek, Connie R.; Carroll, William A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3659 - 3666

403-16-73-氯-4-氟苯甲酸

65055-17-63-氯-4-氟苯甲酰氯

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7042 A1, 2007 ;
Location in patent: Page/Page column 40-41 ;
WO 2007/007042 A1

64-17-5乙醇+

403-16-73-氯-4-氟苯甲酸

137521-81-43-氯-4-氟苯甲酸乙酯

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13138 A2, 2004 ;
Location in patent: Page 21 ;
WO 2004/013138 A2

67-56-1甲醇+

403-16-73-氯-4-氟苯甲酸

234082-35-03-氯-4-氟苯甲酸甲酯

参考文献

SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2006/88919 A2, 2006 ;
Location in patent: Page/Page column 142-143 ;
WO 2006/088919 A2