3-氟-4-硝基苯甲酸合成路线

Howes, Peter D.; Cleasby, Anne; Evans, Derek N.; Feilden, Helen; Smith, Paul W.; Sollis, Steven L.; Taylor, Neil; Wonacott, Alan J.
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 3 p. 225 - 234

403-21-43-氟-4-硝基苯甲酸

157665-52-63-氟-4-硝基苯甲酸叔丁酯

参考文献

Springer; Niculescu-Duvaz; Pedley
Journal of Medicinal Chemistry, 1994 , vol. 37, # 15 p. 2361 - 2370

403-21-43-氟-4-硝基苯甲酸

157665-51-53-氟-4-硝基苯甲酰氯

参考文献

F2G LTD
Patent: WO2009/130481 A1, 2009 ;
Location in patent: Page/Page column 145 ;

79-37-8草酰氯+

403-21-43-氟-4-硝基苯甲酸

157665-51-53-氟-4-硝基苯甲酰氯

参考文献

Bigge, Christopher Franklin; Casimiro-Garcia, Agustin; Dudley, Danette Andrea; Edmunds, Jeremy John; Filipski, Kevin James; Kohrt, Jeffrey Thomas; Van Huis, Chad Alan
Patent: US2003/162787 A1, 2003 ;

403-21-43-氟-4-硝基苯甲酸

3556-52-3

参考文献

Helsby, Nuala A.; Atwell, Graham J.; Yang, Shangjin; Palmer, Brian D.; Anderson, Robert F.; Pullen, Susan M.; Ferry, Dianne M.; Hogg, Alison; Wilson, William R.; Denny, William A.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3295 - 3307

185629-31-63-氟-4-硝基苯甲酸甲酯+

5081-36-73-甲氧基-4-硝基苯甲酸+

403-21-43-氟-4-硝基苯甲酸

185629-32-74-氨基-3-氟苯羧酸甲酯

参考文献

Roche Bioscience, a division of Syntex (U.S.A.) LLC
Patent: US2003/158226 A1, 2003 ;
US 20030158226 A1