2-溴-4'-氟苯乙酮合成路线 （共 119 条）
反应条件
bromine in 1,4-dioxane; diethyl ether 0.5 h; Ambient temperature;
参考文献
Laufer, Stefan A.; Hauser, Dominik R. J.; Liedtke, Andy J.
Synthesis, 2008 , # 2 p. 253 - 266
反应条件
2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; water in 1,2-dichloro-ethane T=20°C; 14 h;
参考文献
Xie, Longyong; Wu, Yundong; Yi, Weiguo; Zhu, Lei; Xiang, Jiannan; He, Weimin
Journal of Organic Chemistry, 2013 , vol. 78, # 18 p. 9190 - 9195
反应条件
dipotassium peroxodisulfate; potassium bromide in water T=60°C; 12 h; Green chemistry;
参考文献
Jiang, Qing; Sheng, Wenbing; Guo, Cancheng
Green Chemistry, 2013 , vol. 15, # 8 p. 2175 - 2179
反应条件
N-bromosuccinmide; trimethylsilyl trifluoromethanesulfonate in acetonitrile T=20°C; 24 h;
参考文献
Guha, Samar Kumar; Wu, Bo; Kim, Beom Soo; Baik, Woonphil; Koo, Sangho
Tetrahedron Letters, 2006 , vol. 47, # 3 p. 291 - 293
反应条件
1: N-bromosuccinmide; silver nitrate / acetone / 20 °C 2: water; 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide / 1,2-dichloro-ethane / 14 h / 20 °C View Scheme
参考文献
Xie, Longyong; Wu, Yundong; Yi, Weiguo; Zhu, Lei; Xiang, Jiannan; He, Weimin
Journal of Organic Chemistry, 2013 , vol. 78, # 18 p. 9190 - 9195
反应条件
1: NaH / tetrahydrofuran / 0.5 h / Ambient temperature 2: acetic anhydride / 0.25 h / 40 °C View Scheme
参考文献
Ogata, Masaru; Matsumoto, Hiroshi; Kida, Shiro; Shimizu, Sumio; Tawara, Katsuya; Kawamura, Yoshimi
Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1497 - 1502
反应条件
sodium carbonate; 1-n-butyl-3-methylimidazolium tetrafluoroborate T=25°C; 1 h;
参考文献
Xie, Yuan-Yuan; Chen, Zhen-Chu; Zheng, Qin-Guo
Journal of Chemical Research - Part S, 2003 , # 10 p. 614 - 615
反应条件
1: acetone / |Reflux 2: hydrogenchloride / water / 1 h / |Reflux View Scheme
参考文献
Kamal, Ahmed; Reddy, Vangala Santhosh; Karnewar, Santosh; Chourasiya, Sumit S.; Shaik, Anver Basha; Kumar, G. Bharath; Kishor, Chandan; Reddy, M. Kashi; Narasimha Rao; Nagabhushana, Ananthamurthy; Ramakrishna, Kallaganti V. S.; Addlagatta, Anthony; Kotamraju, Srigiridhar
ChemMedChem, 2013 , vol. 8, # 12 p. 2015 - 2025
反应条件
1: 0.02 h / 100 °C / Microwave irradiation; Neat (no solvent) 2: urea / 150 °C / Microwave irradiation; Neat (no solvent) View Scheme
参考文献
Motevalli, Kourosh; Yaghoubi, Zahra; Mirzazadeh, Roghieh
E-Journal of Chemistry, 2012 , vol. 9, # 3 p. 1047 - 1052
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane in chloroform T=20°C; 17 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/50627 A1, 2004 ;
Location in patent: Page 15 ;
WO 2004/050627 A1
