4’-氟-2-羟基苯乙酮合成路线 （共 16 条）
反应条件
sodium ethanolate in ethanol
参考文献
Kaspersen, Svein Jacob; Hoff, Bard Helge; Sundby, Eirik; Charnock, Colin
Bioorganic Chemistry, 2012 , vol. 44, p. 35 - 41,7
参考文献
Wang, You-Qing; Yu, Chang-Bin; Wang, Da-Wei; Wang, Xiao-Bing; Zhou, Yong-Gui
Organic Letters, 2008 , vol. 10, # 10 p. 2071 - 2074
反应条件
pyridine; formic acid; chlorosulphonyl isocyanate in acetonitrile T=0 - 10°C; Inert atmosphere;
参考文献
Wang, You-Qing; Yu, Chang-Bin; Wang, Da-Wei; Wang, Xiao-Bing; Zhou, Yong-Gui
Organic Letters, 2008 , vol. 10, # 10 p. 2071 - 2074
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide T=80°C; 2 h;
参考文献
Zhu, Yan-Ping; Jia, Feng-Cheng; Liu, Mei-Cai; Wu, An-Xin
Organic Letters, 2012 , vol. 14, # 17 p. 4414 - 4417
反应条件
1: potassium tert-butylate / tetrahydrofuran / 6 h / 80 °C / |Inert atmosphere 2: sulfuric acid / 1 h / 100 °C / |Inert atmosphere View Scheme
参考文献
Ghani, Sherif B. Abdel; Mugisha, Patrick J.; Wilcox, Juliet C.; Gado, Emad A. M.; Medu, Erere O.; Lamb, Andrew J.; Brown, Richard C. D.
Synthetic Communications, 2013 , vol. 43, # 11 p. 1549 - 1556
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane; acetonitrile
T=20°C; 10 h;
参考文献
Zhejiang Hisun Pharmaceutical Co. Ltd.
Patent: EP2465847 A1, 2012 ;
Location in patent: Page/Page column 14; 15; 16 ;
