1-(4-氟苯基)-1-乙醇合成路线 （共 81 条）
反应条件
hydrogen; Ru(1,3-dimesityl-2,3-dihydro-1H-imidazol-2-yl)(PPh3)2CO(H)2 in benzene T=70°C; P=3800 Torr; 24 h;
参考文献
Battilocchio, Claudio; Hawkins, Joel M.; Ley, Steven V.
Organic Letters, 2013 , vol. 15, # 9 p. 2278 - 2281
反应条件
[RuCl2(triphenylphosphine)((6-((3,5-dimethyl-pyrazol-1-yl)pyridin-2-yl)methylene)-p-tolyl-amine)]*0.5Et2O; potassium isopropoxide T=82°C; P=750.075 Torr; 0.666667 h; Inert atmosphere;
参考文献
Zhao, Miao; Yu, Zhengkun; Yan, Shenggang; Li, Yang
Journal of Organometallic Chemistry, 2009 , vol. 694, # 19 p. 3068 - 3075
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol T=20°C; 17 h;
参考文献
Yamamoto, Takeshi; Suginome, Michinori
Angewandte Chemie - International Edition, 2009 , vol. 48, # 3 p. 539 - 542
反应条件
1: With 1-bromo-butane; sodium tetrahydroborate; Aliquatreg; 336 T=20°C; Addition; Hydroboration; 16 h; 2: With sodium hydroxide; dihydrogen peroxide T=40°C; Oxidation; 1 h;
参考文献
Ramachandran, P. Veeraraghavan; Madhi, Sateesh; O'Donnell, Martin J.
Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1252 - 1255
反应条件
cerium(III) sulphate; barium bromate in water; acetonitrile 2.2 h; Heating; Title compound not separated from byproducts;
参考文献
Shaabani, Ahmad; Lee, Donald G.
Synthetic Communications, 2003 , vol. 33, # 11 p. 1845 - 1854
反应条件
1: With formic acid T=100°C; 5 h; Inert atmosphereSealed tube; 2: With chloro-(pentamethylcyclopentadienyl)-{5-methoxy-2-{1-[(4-methoxyphenyl)imino-N]ethyl}phenyl-C}-iridium(lll); water; sodium formate T=20 - 80°C; pH=3.5; 6 h;
参考文献
Li, Jia; Wang, Chao; Xue, Dong; Wei, Yawen; Xiao, Jianliang
Green Chemistry, 2013 , vol. 15, # 10 p. 2685 - 2689
反应条件
sulfuric acid T=25°C; Rate constant;
参考文献
McEwen, John; Yates, Keith
Journal of the American Chemical Society, 1987 , vol. 109, # 19 p. 5800 - 5808
反应条件
in diethyl ether Heating;
参考文献
Hatzakis, Nikos S.; Smonou, Ioulia
Bioorganic Chemistry, 2005 , vol. 33, # 4 p. 325 - 337
反应条件
1: AlCl3; carbon disulfide 2: copper oxide-chromium oxide / 132 °C / 84583.4 Torr / Hydrogenation View Scheme
参考文献
Gruenenthal GmbH
Patent: US2012/46301 A1, 2012 ;
US 20120046301 A1
参考文献
Solomon,I.J.; Filler,R.
Journal of the American Chemical Society, 1963 , vol. 85, p. 3492 - 3496
