1-(4-氟苯基)-1-乙醇合成路线 （共 81 条）
反应条件
in hydrogenchloride; ethanol; butan-1-ol Ambient temperaturecathode: Pb plate (ca. 21.3 cm2); Pt plate (ca. 4.0 cm2), constant current density (-3.7 mA/cm2);
参考文献
Ikeda, Yoshikazu
Chemistry Letters, 1990 , # 9 p. 1719 - 1720
反应条件
trimethyltelluronium iodide 1.) hexane, THF, -60 deg C, 10 min, 2.) -78 deg C -> RT; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Shi, Li-Lan; Zhou, Zhang-Lin; Huang, Yao-Zeng
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 10 p. 2847 - 2848
反应条件
n-butyllithium 1.) hexane, THF, -60 deg C, 10 min, 2.) -78 deg C -> RT; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Shi, Li-Lan; Zhou, Zhang-Lin; Huang, Yao-Zeng
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 10 p. 2847 - 2848
反应条件
perchloric acid; sodium perchlorate; water Ambient temperature; Product distribution;
参考文献
Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1373 - 1383
反应条件
perchloric acid; sodium perchlorate; water Ambient temperature; Product distribution;
参考文献
Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1373 - 1383
参考文献
Taylor, Roger
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 737 - 744
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 16 h / 20 °C 2.1: sodium tetrahydroborate; selenium / N,N-dimethyl-formamide; ethanol / 3.33 h / 20 °C 2.2: 3 h / 20 °C 3.1: Thermobifida fusca recombinant phenylacetone monooxygenase; phosphite dehydrogenase; NADPH; sodium phosphite / dimethyl sulfoxide / 5 h / 30 °C / pH 7.5 / |Enzymatic reaction View Scheme
参考文献
Brondani, Patricia B.; Guilmoto, Nathalie M. A. F.; Andrade, Leandro H.; Dudek, Hanna M.; Fraaije, Marco W.
Tetrahedron, 2012 , vol. 68, # 51 p. 10431 - 10436,6
Title/Abstract Full Text Show Details
Brondani, Patricia B.; Guilmoto, Nathalie M.A.F.; Dudek, Hanna M.; Fraaije, Marco W.; Andrade, Leandro H.
Tetrahedron, 2012 , vol. 68, # 51 p. 10431 - 10436
反应条件
[Ir(η5-C5Me5)(C6H4-2-CH2NHCH3)(NCCH3)](PF6); potassium tert-butylate in toluene T=20°C; 4 h; Inert atmosphere;
参考文献
Jerphagnon, Thomas; Gayet, Arnaud J.A.; Berthiol, Florian; Ritleng, Vincent; Mrsic, Natasa; Meetsma, Auke; Pfeffer, Michel; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G.
Chemistry - A European Journal, 2009 , vol. 15, # 46 p. 12780 - 12790
反应条件
1: With oxygen; sodium hydride in tetrahydrofuran T=0 - 20°C; 6 h; 2: With hydrogenchloride in water
参考文献
Wang, Xinbo; Wang, David Zhigang
Tetrahedron, 2011 , vol. 67, # 19 p. 3406 - 3411
反应条件
ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride; oct-1-ene; dcype in dimethyl sulfoxide T=115°C; 24 h; Inert atmosphere; Reagent/catalyst;
参考文献
Watson, Andrew J. A.; Atkinson, Benjamin N.; Maxwell, Aoife C.; Williams, Jonathan M. J.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 734 - 740
