1: Methyltriphenylphosphonium bromide With potassium tert-butylate in tetrahydrofuran T=0°C; 1 h; 2: 1-fluoro-4-acetyl-benzene in tetrahydrofuran Wittig olefination; Further stages.;
参考文献
Sherrill, William M.; Kim, Ryan; Rubin, Michael
Tetrahedron, 2008 , vol. 64, # 37 p. 8610 - 8617
1: With ammonium acetate; sodium cyanoborohydride in methanol T=20°C; reductive amination; 2: racemate resolution; Further stages. Title compound not separated from byproducts.;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , # 7 p. 1339 - 1347