Lang, Lixin; Jagoda, Elaine; Schmall, Bernard; Vuong, Bik-Kee; Adams, H. Richard; Nelson, David L.; Carson, Richard E.; Eckelman, William C.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 9 p. 1576 - 1586
1.1: sodium hydrogencarbonate / 2-methyl tetrahydrofuran; water / 0.5 h / Cooling
1.2: 3 h / 10 °C / Cooling
2.1: water; sodium hydroxide / 2-methyl tetrahydrofuran / 1 h / 25 - 28 °C
View Scheme
参考文献
Chavez, Flavio; Kennedy, Nicole; Rawalpally, Thimma; Williamson, R. Thomas; Cleary, Thomas
Organic Process Research and Development, 2010 , vol. 14, # 3 p. 579 - 584