1-二苯甲基氮杂环丁烷-3-酮合成路线 （共 23 条）
反应条件
1: With cesium fluoride in tetrahydrofuran
T=23°C; 0.25 h;
2: With tetrabutyl ammonium fluoride; water; ammonium chloride in tetrahydrofuran
24 h;
参考文献
WARNER-LAMBERT COMPANY LLC; ELLSWORTH, Edmund, Lee
Patent: WO2005/26153 A1, 2005 ;
Location in patent: Page 43-44 ;
反应条件
hydrogen; palladium on activated carbon in methanol; water
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1762568 A1, 2007 ;
Location in patent: Page/Page column 37 ;
反应条件
1: triphenyl-methyl-phosphonium iodide With potassium tert-butylate in dimethyl sulfoxide
T=25°C; 1.25 h;
2: 1-(1,1-diphenylmethyl)azetidin-3-one in dimethyl sulfoxide
T=60°C; 18 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/141473 A1, 2007 ;
Location in patent: Page/Page column 236 ;
WO 2007/141473 A1
