单(2-乙基-5-氧己基)邻苯二甲酸酯合成路线 （共 12 条）
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane
T=-65°C; Swern oxidation; 0.5 h;
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
p-benozquinone; palladium dichloride in water; N,N-dimethyl-formamide
T=20°C;
参考文献
Nuti, Francesca; Hildenbrand, Sibylle; Chelli, Mario; Wodarz, Roman; Papini, Anna Maria
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 10 p. 3461 - 3465
反应条件
1: 94 percent / pyridine / 3 h / Heating
2: 41 percent / p-benzoquinone; PdCl2 / dimethylformamide; H2O / 20 °C
View Scheme
参考文献
Nuti, Francesca; Hildenbrand, Sibylle; Chelli, Mario; Wodarz, Roman; Papini, Anna Maria
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 10 p. 3461 - 3465
反应条件
1: 94 percent / pyridine / 3 h / Heating
2: 41 percent / p-benzoquinone; PdCl2 / dimethylformamide; H2O / 20 °C
View Scheme
参考文献
Nuti, Francesca; Hildenbrand, Sibylle; Chelli, Mario; Wodarz, Roman; Papini, Anna Maria
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 10 p. 3461 - 3465
反应条件
1: 77 percent / NaBH4 / ethanol / 2 h / 20 °C
2: 68 percent / imidazole / dimethylformamide / 3 h / 20 °C
3: 88 percent / imidazole; 4-dimethylaminopyridine / CH2Cl2 / 17 h / 20 °C
4: 76 percent / pyridinium p-toluenesulfonate / ethanol / 66 h / 20 °C
5: 86 percent / pyridine / 72 h / 20 °C
6: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
7: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
1: 68 percent / imidazole / dimethylformamide / 3 h / 20 °C
2: 88 percent / imidazole; 4-dimethylaminopyridine / CH2Cl2 / 17 h / 20 °C
3: 76 percent / pyridinium p-toluenesulfonate / ethanol / 66 h / 20 °C
4: 86 percent / pyridine / 72 h / 20 °C
5: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
6: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
1: 88 percent / imidazole; 4-dimethylaminopyridine / CH2Cl2 / 17 h / 20 °C
2: 76 percent / pyridinium p-toluenesulfonate / ethanol / 66 h / 20 °C
3: 86 percent / pyridine / 72 h / 20 °C
4: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
5: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
1: 86 percent / pyridine / 72 h / 20 °C
2: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
3: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
1: 76 percent / pyridinium p-toluenesulfonate / ethanol / 66 h / 20 °C
2: 86 percent / pyridine / 72 h / 20 °C
3: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
4: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
反应条件
1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 72 h / 20 °C
2: 56 percent / oxalyl chloride; DMSO; Et3N / CH2Cl2 / 0.5 h / -65 °C
View Scheme
参考文献
Gilsing, Hans-Detlev; Angerer, Juergen; Prescher, Dietrich
Monatshefte fur Chemie, 2002 , vol. 133, # 8 p. 1147 - 1155
