2,3,4,5-四氢-1,5-苯并噻氮杂卓合成路线 （共 7 条）
反应条件
aluminum dichloride hydride in CPME
T=0 - 20°C; 2.25 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Mitsuhashi, Nakako; Sugimoto, Kenji; Okano, Kentaro; Tokuyama, Hidetoshi
Molecules, 2012 , vol. 17, # 6 p. 7348 - 7355
反应条件
aluminum dichloride hydride in diethyl ether
T=0 - 20°C; 2 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Mitsuhashi, Nakako; Sugimoto, Kenji; Okano, Kentaro; Tokuyama, Hidetoshi
Molecules, 2012 , vol. 17, # 6 p. 7348 - 7355
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane
T=0 - 20°C; 2.25 h; Inert atmosphere;
2: With NAF in hexane; dichloromethane; water
T=0°C; 0.5 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Sugimoto, Kenji; Kwon, Eunsang; Tokuyama, Hidetoshi
Heterocycles, 2009 , vol. 78, # 5 p. 1183 - 1190
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane
T=0°C; 3.5 h; Inert atmosphere;
2: With NAF in hexane; dichloromethane; water
T=0°C; 0.5 h; Inert atmosphere; regiospecific reaction;
参考文献
Cho, Hidetsura; Sugimoto, Kenji; Iwama, Yusuke; Mitsuhashi, Nakako; Okano, Kentaro; Tokuyama, Hidetoshi
Heterocycles, 2011 , vol. 82, # 2 p. 1633 - 1644
反应条件
1.1: NaH / hexane; tetrahydrofuran / 0.5 h / 20 °C
1.2: 87 percent / hexane; tetrahydrofuran / 6 h / 20 °C
2.1: 85 percent / diisopropylamine; n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C
View Scheme
参考文献
Mukherjee, Chandrani; Biehl, Ed
Heterocycles, 2004 , vol. 63, # 10 p. 2309 - 2318
参考文献
Muschkalo; Fedorowa
Ukrainskii Khimicheskii Zhurnal (Russian Edition), 1954 , vol. 20, p. 305
Chem.Abstr., 1956 , p. 366
反应条件
hydrogenchloride in diethyl ether
T=20°C;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Mitsuhashi, Nakako; Sugimoto, Kenji; Okano, Kentaro; Tokuyama, Hidetoshi
Molecules, 2012 , vol. 17, # 6 p. 7348 - 7355
