1: 2,3-dihydroindole With triethylamine in dichloromethane T=0°C; 0.0833333 h; Inert atmosphere; 2: 6-bromopiperonylic chloride in dichloromethane; toluene T=0 - 20°C; Inert atmosphere;

1.1: thionyl chloride / toluene; N,N-dimethyl-formamide / 2.92 h / 0 - 80 °C / |Inert atmosphere 2.1: triethylamine / dichloromethane / 0.08 h / 0 °C / |Inert atmosphere 2.2: 0 - 20 °C / |Inert atmosphere View Scheme

potassium tert-butylate; N,N-dimethylethylenediamine in 1,3,5-trimethyl-benzene T=100°C; 5 h; Inert atmosphere;