反应条件
1: ethyl (2R,3R,4S)-(+)-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)pyrrolidine-3-carboxylate, (S)-(+) mandelate With sodium hydrogencarbonate in water; ethyl acetate T=25°C; 2: BrCH2CONBu2; N-ethyl-N,N-diisopropylamine in ethyl acetate; acetonitrile T=110°C; 16 h;