1,4-二噁-7-氮杂螺[4.5]癸烷合成路线 （共 2 条）
反应条件
toluene-4-sulfonic acid in toluene
7 h; Heating / refluxDean-Stark apparatus;
参考文献
OSI PHARMACEUTICALS, INC.
Patent: WO2004/104001 A2, 2004 ;
Location in patent: Page 65 ;
WO 2004/104001 A2
反应条件
1: HCl / CHCl3
2: H2 / Pd-C / methanol
View Scheme
参考文献
Arya,V.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15B, p. 635 - 640
