反应条件
1: 930 mg / H2, HCl / 10percent Pd/C / 18 h / 2585.7 Torr
2: 1 M LiOH / 1,2-dimethoxy-ethane / 18 h / Ambient temperature
View Scheme
参考文献
Tucker, Thomas J.; Lumma, William C.; Dale Lewis; Gardell, Stephen J.; Lucas, Bobby J.; Sisko, Jack T.; Lynch, Joseph J.; Lyle, Elizabeth A.; Baskin, Elizabeth P.; Woltmann, Richard F.; Appleby, Sandra D.; Chen, I.-Wu; Dancheck, Kimberley B.; Naylor-Olsen, Adel M.; Krueger, Julie A.; Cooper, Carolyn M.; Vacca, Joseph P.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 22 p. 3687 - 3693