1.1: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C 2.1: HCO2H; Et3N / Pd(Ph3P)4 / tetrahydrofuran / 7 h / 20 °C 2.2: NaOH / tetrahydrofuran; methanol / 15 h / 20 °C View Scheme

1: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C 2: BuZnCl / Pd(Ph3P)4 / tetrahydrofuran / 2 h / Heating View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '108808', constants.ctx, '0')">1,3-dimethyl-imidazolidin-2-one</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a> <br />T=20&deg;C;&nbsp;2&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 10 percent / N,N'-dimethylimidazolidinone; H₂O; InI / Pd(Ph₃P)4 / 48 h / 20 &deg;C<br />2: 87 percent / N,N'-dimethylimidazolidinone; aq. HCl / 2 h / 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 10 percent / N,N'-dimethylimidazolidinone; H₂O; InI / Pd(Ph₃P)4 / 48 h / 20 &deg;C<br />2: 87 percent / N,N'-dimethylimidazolidinone; aq. HCl / 2 h / 20 &deg;C<br /> <br /> &nbsp;