2-溴-4-甲基-1-硝基苯合成路线 （共 18 条）
反应条件
1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide; water / 5 h / 80 °C / |Inert atmosphere 2: phenyl-magnesium bromide / tetrahydrofuran / 0.25 h / 0 °C / |Inert atmosphere View Scheme
参考文献
Gao, Hongyin; Xu, Qing-Long; Yousufuddin, Muhammed; Ess, Daniel H.; Kuerti, Laszlo
Angewandte Chemie - International Edition, 2014 , vol. 53, # 10 p. 2701 - 2705
Angew. Chem., 2014 , vol. 53, # 10 p. 2739 - 2743,5
反应条件
1: 78 percent / PPh3 / Pd(dba)2 / toluene / 19 h / Heating 2: 51 percent / PPh3, CO / Pd(OAc)2 / acetonitrile / 72 h / 3040 Torr / Heating View Scheme
参考文献
Kasahara, Akira; Izumi, Taeko; Murakami, Satoshi; Miyamoto, Kazuhiro; Hino, Toshimi
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1405 - 1413
反应条件
1: CrO3; acetic acid 2: HCl View Scheme
参考文献
Rieger; Westheimer
Journal of the American Chemical Society, 1950 , vol. 72, p. 28,30
反应条件
chromium(VI) oxide; sulfuric acid; acetic anhydride in ethanol; water 1 h; Heating;
参考文献
Rama Rao; Chakraborty; Laxma Reddy; Srinivasa Rao
Tetrahedron Letters, 1992 , vol. 33, # 33 p. 4799 - 4802
反应条件
chromium(VI) oxide; acetic acid
参考文献
Rieger; Westheimer
Journal of the American Chemical Society, 1950 , vol. 72, p. 28,30
反应条件
1: ethanol; dimethylsulfoxide 2: NaOH / dimethylformamide View Scheme
参考文献
Fletcher; Namkung; Pan; Cole
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1113 - 1115
反应条件
1: ethanol; dimethylsulfoxide 2: NaOH / dimethylformamide 3: N2H4*H2O / Pd-C / ethanol View Scheme
参考文献
Fletcher; Namkung; Pan; Cole
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1113 - 1115
参考文献
Rieger; Westheimer
Journal of the American Chemical Society, 1950 , vol. 72, p. 28,30
