反应条件
1: 86 percent / LiAlH4 / diethyl ether / 15 h / Ambient temperature 2: Et3N / CH2Cl2 / 1.) 0 deg C, 30 min, 2.) RT, 1 h 3: 1.) NaH, 2.) KI / 1.) DMF, THF, RT, 15 min, 2.) DMF, THF, 80 deg C, 3.5 h 4: 86 percent / DMSO, NaCl / H2O / 3 h / 170 °C 5: 92 percent / aq. NaOH / methanol / 15 h / Heating 6: SOCl2 / 2 h / Heating 7: diethyl ether / 2 h / Heating View Scheme
参考文献
Kaga, Harumi; Goto, Kouhei; Takahashi, Tomiki; Hino, Masao; Tokuhashi, Takashi; Orito, Kazuhiko
Tetrahedron, 1996 , vol. 52, # 25 p. 8451 - 8470
