(4S)-4-甲基-2-噁唑烷酮合成路线 （共 9 条）
反应条件
caesium carbonate in dimethylsulfoxide-d6
T=25 - 150°C; P=2280.15 Torr; 24 h; Autoclave;
参考文献
Foo, Siong Wan; Takada, Yuki; Yamazaki, Yusuke; Saito, Susumu
Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4717 - 4720
反应条件
triethylamine in tetrahydrofuran
T=20 - 60°C;
参考文献
ACADIA PHARMACEUTICALS INC.
Patent: WO2004/808 A2, 2003 ;
Location in patent: Page 78 ;
WO 2004/000808 A2
反应条件
sodium ethanolate
T=95 - 125°C; 8 h;
参考文献
Rein, Kathleen; Goicoechea-Pappas, Marta; Anklekar, Tarakeshwar V.; Hart, Georgina C.; Smith, Gregory A.; Gawley, Robert E.
Journal of the American Chemical Society, 1989 , vol. 111, # 6 p. 2211 - 2217
反应条件
potassium tert-butylate in tetrahydrofuran
T=0°C; 6 h; Inert atmosphere;
参考文献
Adams, Harry; Collins, Rebecca C.; Jones, Simon; Warner, Christopher J. A.
Organic Letters, 2011 , vol. 13, # 24 p. 6576 - 6579
反应条件
[ruthenium(dichloride)(Ph2PC2H4NH2)2]; hydrogen; sodium methylate in tetrahydrofuran
T=80°C; P=37503.8 Torr; 16 h; Autoclave;
参考文献
Kuriyama, Wataru; Ino, Yasunori; Ogata, Osamu; Sayo, Noboru; Saito, Takao
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 1 p. 92 - 96
反应条件
methyloxirane
T=100°C; 48 h; Inert atmosphere;
参考文献
Minor-Villar, Leticia; Tello-Aburto, Rodolfo; Olivo, Horacio F.; Fuentes, Aydee; Romero-Ortega, Moises
Synlett, 2012 , vol. 23, # 19 p. 2835 - 2839
反应条件
potassium carbonate in tetrahydrofuran
15 h; Reflux;
参考文献
Veeraswamy; Reddy, K. Indrasena; Ragavan, R. Venkat; Yennam, Satyanarayana; Jayashree
Chemistry Letters, 2013 , vol. 42, # 2 p. 109 - 111
反应条件
1: (L)-alanine methyl ester With lithium aluminium tetrahydride in diethyl ether
2: carbonic acid diethyl ester With potassium ethanolate in tetrahydrofuran
参考文献
Davies, Iwan R.; Cheeseman, Matt; Niyadurupola, D. Gangani; Bull, Steven D.
Tetrahedron Letters, 2005 , vol. 46, # 33 p. 5547 - 5549
反应条件
potassium carbonate
T=20°C;
参考文献
Gong, Jing-Jing; Yuan, Kui; Song, Hong-Liang; Wu, Xin-Yan
Tetrahedron, 2010 , vol. 66, # 13 p. 2439 - 2443
