2-溴-5-氯吡啶合成路线

1072-98-62-氨基-5-氯吡啶

40473-01-62-溴-5-氯吡啶

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DAIICHI PHARMACEUTICAL CO., LTD.
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1072-98-62-氨基-5-氯吡啶

40473-01-62-溴-5-氯吡啶+

2516-40-72-溴苯并噻唑

参考文献

Pfizer Inc.
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16110-09-12,5-二氯吡啶

40473-01-62-溴-5-氯吡啶

参考文献

Schlosser, Manfred; Cottet, Fabrice
European Journal of Organic Chemistry, 2002 , # 24 p. 4181 - 4184

4214-79-35-氯-2-羟基吡啶

40473-01-62-溴-5-氯吡啶

参考文献

Jacobsen, Eric Jon; Myers, Jason K.; Walker, Daniel Patrick; Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Acker, Brad A.; Groppi JR., Vincent E.
Patent: US2003/236270 A1, 2003 ;
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40473-01-62-溴-5-氯吡啶

1061357-88-72-溴-4-碘-5-氯吡啶

参考文献

KALYPSYS, INC.
Patent: WO2009/117421 A2, 2009 ;
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WO 2009/117421 A2

40473-01-62-溴-5-氯吡啶

605681-01-42-(溴甲基)-5-氯-吡啶(9ci)

参考文献

GLAXOSMITHKLINE LLC; QIN, Donghui; CHRISTENSEN, IV, Siegfried Benjamin; WU, Chengde; ZHANG, Zhiliu; YU, Haiyu; YUAN, Jiangxing; LIN, Xiaojuan; XU, Shanli; LV, Maoyun; YAO, Chen; LI, Lei; HUANG, Xing; GAO, Min
Patent: WO2013/166621 A1, 2013 ;

40473-01-62-溴-5-氯吡啶

349-94-05-氯-2-三氟甲基吡啶

参考文献

Zhang, Xuqing; Sui, Zhihua; Lanter, James C.
Patent: US2011/306592 A1, 2011 ;

40473-01-62-溴-5-氯吡啶+

127-19-5N,N-二甲基乙酰胺

94952-46-21-(5-氯吡啶-2-基)乙酮

参考文献

F2G LTD
Patent: WO2005/92304 A2, 2005 ;
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40473-01-62-溴-5-氯吡啶

94952-46-21-(5-氯吡啶-2-基)乙酮

参考文献

Sandoz Ltd.
Patent: US5622982 A1, 1997 ;

40473-01-62-溴-5-氯吡啶

87394-65-81-(5-氯-2-哌啶基)哌嗪

参考文献

SK Chemicals Co.,Ltd.; RYU, Je Ho; KIM, Shin Ae; RYU, Keun Ho; KIM, Jae Sun; KIM, Nam Ho; HAN, Hye Young; KIM, Yong Hyuk; YOUN, Won-No; LEE, Yoon-Jung; SON, Hyun Joo; LEE, Bong-yong; PARK, Sung Hoon; LEE, Ju Young; LEE, Hyun Jung; JUNG, Hoe Chul; SHIN, Young Ah; LEE, Jung A; LEE, Bo Ram; SA, Joon Ho
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WO 2011/139107 A2