2-溴-5-氯吡啶合成路线

209526-98-7(5-氯-2-吡啶基)甲醇

参考文献

GLAXOSMITHKLINE LLC; QIN, Donghui; CHRISTENSEN, IV, Siegfried Benjamin; WU, Chengde; ZHANG, Zhiliu; YU, Haiyu; YUAN, Jiangxing; LIN, Xiaojuan; XU, Shanli; LV, Maoyun; YAO, Chen; LI, Lei; HUANG, Xing; GAO, Min
Patent: WO2013/166621 A1, 2013 ;

40473-01-62-溴-5-氯吡啶+

64-17-5乙醇+

201230-82-2

128072-93-55-氯吡啶-2-甲酸乙酯

参考文献

Jacobsen, Eric Jon; Myers, Jason K.; Walker, Daniel Patrick; Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Acker, Brad A.; Groppi JR., Vincent E.
Patent: US2003/236270 A1, 2003 ;
Location in patent: Page 44 ;

40473-01-62-溴-5-氯吡啶+

67-56-1甲醇+

201230-82-2

132308-19-15-氯吡啶-2-羧酸甲酯

参考文献

GLAXOSMITHKLINE LLC; CHRISTENSEN, Siegfried, Benjamin, IV; QIN, Donghui; CHEN, Shenglin; HUANG, Xing; LI, Di; LI, Fei; LI, Lei; LIN, Xiaojuan; LU, Shi; LU, Zhen; LV, Maoyun; WANG, Chuanning; WU, Chengde; XIAO, Mei; YU, Haiyu; ZHANG, Weina; ZHANG, Zhiliu
Patent: WO2010/141539 A1, 2010 ;
Location in patent: Page/Page column 18 ;

40473-01-62-溴-5-氯吡啶

823221-95-0

参考文献

Zhang, Xuqing; Sui, Zhihua; Lanter, James C.
Patent: US2011/306592 A1, 2011 ;

40473-01-62-溴-5-氯吡啶

823221-96-1

参考文献

Zhang, Xuqing; Sui, Zhihua; Lanter, James C.
Patent: US2011/306592 A1, 2011 ;

40473-01-62-溴-5-氯吡啶+

79-44-7二甲氨基甲酰氯

89544-38-7

参考文献

Pfizer Inc.
Patent: US4529799 A1, 1985 ;

40473-01-62-溴-5-氯吡啶+

68-12-2N,N-二甲基甲酰胺

921630-14-02-溴-5-氯吡啶-4-甲醛

参考文献

Bezencon, Olivier; Bur, Daniel; Corminboeuf, Olivier; Dube, Daniel; Grisostomi, Corinna; MacDonald, Dwight; McKay, Dan; Powell, David; Remen, Lubos; Richard-Bildstein, Sylvia; Scheigetz, John; Therien, Michel; Weller, Thomas
Patent: US2009/176823 A1, 2009 ;
Location in patent: Page/Page column 16 ;

40473-01-62-溴-5-氯吡啶+

174669-73-92-氟-3-吡啶硼酸

942206-10-25-氯-2’-氟-2,3’-联吡啶

参考文献

Voisin-Chiret, Anne Sophie; Bouillon, Alexandre; Burzicki, Gregory; Celant, Melanie; Legay, Remi; El-Kashef, Hussein; Rault, Sylvain
Tetrahedron, 2009 , vol. 65, # 3 p. 607 - 612