4-氯甲基-N-[4-甲基-3-[[4-(吡啶-3-基)嘧啶-2-基]氨基]苯基]苯甲酰胺合成路线 （共 12 条）
反应条件
1.1: thionyl chloride / dichloromethane / 5 h / |Reflux; |Inert atmosphere; |Schlenk technique 2.1: triethylamine / tetrahydrofuran / 0.17 h / 0 °C / |Inert atmosphere; |Schlenk technique 2.2: 3.17 h / 0 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Liu, Yi-Feng; Wang, Cui-Ling; Bai, Ya-Jun; Han, Ning; Jiao, Jun-Ping; Qi, Xiao-Li
Organic Process Research and Development, 2008 , vol. 12, # 3 p. 490 - 495
反应条件
in 1,4-dioxane T=135°C; 3 h; Conversion of starting material;
参考文献
Ingham, Richard J.; Riva, Elena; Nikbin, Nikzad; Baxendale, Ian R.; Ley, Steven V.
Organic Letters, 2012 , vol. 14, # 15 p. 3920 - 3923
