(2,2-二氟乙烯基)苯合成路线 （共 44 条）
反应条件
1: 49 percent / chlorotrimethylsilane / tetrahydrofuran; hexane / 1.) -78 deg C, 5 h; 2.) to r.t., overnight
2: 28 percent / n-dodecane, CsF / dimethylformamide / 4 h / 100 °C
View Scheme
参考文献
Okano,T.; Ito,K.; Ueda,T.
Journal of Fluorine Chemistry, 1986 , vol. 32, p. 377
反应条件
mercury; zinc
T=-10 - 0°C;
参考文献
England,D.C.; Krespan,C.G.
Journal of Organic Chemistry, 1968 , vol. 33, # 2 p. 816 - 819
反应条件
in N,N-dimethyl-formamide
electrochemical reduction;
参考文献
Auguste, Maxime; Jubault, Philippe; Feasson, Christian; Collignon, Noel
Phosphorus, Sulfur and Silicon and the Related Elements, 1993 , vol. 77, # 1-4 p. 176
反应条件
1: 89 percent / NaBH4 / methanol / Ambient temperature
2: 83 percent / SOCl2, pyridine / benzene / 2 h / Heating
3: zinc / ethanol / 10 h / Heating
View Scheme
参考文献
Okano,T.; Ito,K.; Ueda,T.
Journal of Fluorine Chemistry, 1986 , vol. 32, p. 377
反应条件
acetamide; copper; zinc
T=120°C;
参考文献
Nad' et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959 , p. 272,276; engl. Ausg. S. 250, 254
反应条件
1: triethylamine / tetrahydrofuran / 24 h
2: 67 percent / H2O, butyllithium, cuprous iodide / tetrahydrofuran; various solvent(s) / 1 h / -60 °C
View Scheme
参考文献
Ishihara, Takashi; Yamana, Masayuki; Ando, Teiichi
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5657 - 5660
反应条件
sodium hydride in tetrahydrofuran
var. bases;
参考文献
Obayashi, Michio; Ito, Eiji; Matsui, Kiyohide; Kondo, Kiyosi
Tetrahedron Letters, 1982 , vol. 23, # 22 p. 2323 - 2326
反应条件
potassium fluoride; 18-crown-6 ether in tetrahydrofuran
60 h; Ambient temperature;
参考文献
Okano,T.; Ito,K.; Ueda,T.
Journal of Fluorine Chemistry, 1986 , vol. 32, p. 377
反应条件
1: 90 percent / Et3N; 4-N,N-dimethylaminopyridine / CH2Cl2 / 2 h / 0 °C
2: 60 percent / Na/Hg amalgam; Na2HPO4 / methanol / 1 h / -20 °C
View Scheme
参考文献
Surya Prakash; Wang, Ying; Hu, Jinbo; Olah, George A.
Journal of Fluorine Chemistry, 2005 , vol. 126, # 9-10 p. 1361 - 1367
反应条件
1: 83 percent / SOCl2, pyridine / benzene / 2 h / Heating
2: zinc / ethanol / 10 h / Heating
View Scheme
参考文献
Okano,T.; Ito,K.; Ueda,T.
Journal of Fluorine Chemistry, 1986 , vol. 32, p. 377
