4-氟苯乙酸合成路线

参考文献

Liu, Gai-Zhi; Xu, Hai-Wei; Wang, Peng; Lin, Zong-Tao; Duan, Ying-Chao; Zheng, Jia-Xin; Liu, Hong-Min
European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 323 - 336

121-44-8三乙胺+

50413-24-62-溴-1-(4-甲磺酰基)苯乙酮+

405-50-54-氟苯乙酸

157672-00-9

参考文献

Merck and Co., Inc.
Patent: US5663195 A1, 1997 ;

405-50-54-氟苯乙酸

163563-23-3

参考文献

Samanta, Anuva; Paul, Bijan Kumar; Kar, Samiran; Guchhait, Nikhil
Journal of Fluorescence, 2011 , vol. 21, # 1 p. 95 - 104

405-50-54-氟苯乙酸

192508-36-44-氟-3-硝基苯乙酸

参考文献

DECIPHERA PHARMACEUTICALS, LLC; ELI LILLY AND COMPANY; FLYNN, Daniel L.; KAUFMAN, Michael D.; VOGETI, Lakshminarayana; WISE, Scott C.; LU, Wei-Ping; SMITH, Bryan D.; CALDWELL, Timothy M.; PATT, William C.; HENRY, James Robert; HIPSKIND, Philip Arthur; PENG, Sheng-Bin
Patent: WO2013/134298 A1, 2013 ;
Location in patent: Page/Page column 35 ;

405-50-54-氟苯乙酸

29419-14-56-氟-3,4-二氢-1H-2-萘酮

参考文献

Ortho-McNeil Pharmaceutical, Inc.
Patent: US6140354 A1, 2000 ;

54509-73-8+

405-50-54-氟苯乙酸

29419-14-56-氟-3,4-二氢-1H-2-萘酮

参考文献

Ortho-McNeil Pharmaceutical, Inc.
Patent: EP1076644 B1, 2004 ;
Location in patent: Page 33-34; 36 ;
EP 1076644 B1

405-50-54-氟苯乙酸

221121-37-54-(4-氟苯基)-3-氧代丁酸乙酯

参考文献

Terai, Takuya; Kikuchi, Kazuya; Iwasawa, Shin-Ya; Kawabe, Takao; Hirata, Yasunobu; Urano, Yasuteru; Nagano, Tetsuo
Journal of the American Chemical Society, 2006 , vol. 128, # 21 p. 6938 - 6946

79-02-7二氯乙醛+

405-50-54-氟苯乙酸

1212-25-5N-(2,2-二氯-1-羟基乙基)-2-(4-氟苯基)乙酰胺

参考文献

Jordin; Easterly Jr.; Winningham; Hubbard
Journal of pharmaceutical sciences, 1965 , vol. 54, # 8 p. 1190 - 1193

405-50-54-氟苯乙酸

29270-33-5α-溴-4-氟苯乙酸

参考文献

Cecchetti, Violetta; Fravolini, Arnaldo; Pagella, Pier Giuseppe; Savino, Angela; Tabarrini, Oriana
Journal of Medicinal Chemistry, 1993 , vol. 36, # 22 p. 3449 - 3454

405-50-54-氟苯乙酸

71783-54-5溴(4-氟苯基)乙酸甲酯

参考文献

Pfizer Limited; PFIZER INC.
Patent: EP424021 A1, 1991 ;