3-碘甲基哌啶-1-羧酸苄酯合成路线 （共 3 条）
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane
T=20°C; 4 h;
参考文献
Georgetown University Office of Technology Commercialization
Patent: US2010/48606 A1, 2010 ;
Location in patent: Page/Page column 32 ;
反应条件
1: 94 percent / Et3N / CH2Cl2 / 20 °C
2: 97 percent / PPh3; I2; imidazole / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Chellappan, Sheela K.; Xiao, Yingxian; Tueckmantel, Werner; Kellar, Kenneth J.; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2673 - 2676
反应条件
1: 94 percent / Et3N / CH2Cl2 / 20 °C
2: 97 percent / PPh3; I2; imidazole / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Chellappan, Sheela K.; Xiao, Yingxian; Tueckmantel, Werner; Kellar, Kenneth J.; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2673 - 2676
