3-(2-乙氧基羰基-乙基)-5-甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 5 条）
反应条件
1: 32 percent / H2, Et3N / 10percent Pd/C / aq. ethanol / 5 h / 1471.02 Torr 2: 2.2 g / Cu(OAc)2, quinoline / 3 h / 190 - 210 °C View Scheme
参考文献
MacDonald
Journal of the Chemical Society, 1952 , p. 4176,4182
参考文献
Treibs; Hintermeier
Chemische Berichte, 1954 , vol. 87, p. 1163,1166
反应条件
1: concentrated aqueous HCl / anschliessend Erwaermen mit Acetessigsaeure-tert-butylester, Essigsaeure, Zink-Pulver und Ammoniumacetat 2: aqueous acetic acid 3: toluene-4-sulfonic acid / 240 - 250 °C View Scheme
参考文献
MacDonald
Journal of the Chemical Society, 1952 , p. 4176,4182
反应条件
1: aqueous acetic acid 2: toluene-4-sulfonic acid / 240 - 250 °C View Scheme
参考文献
Treibs; Hintermeier
Chemische Berichte, 1954 , vol. 87, p. 1163,1166
反应条件
1: 86 percent / 8percent aq. NaOH / aq. ethanol / 1 h / Heating
2: 85 percent / H2O / 100 °C
View Scheme
参考文献
Marks et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 3183,3187
Journal of the American Chemical Society, 1959 , vol. 81, p. 250
