2-(乙氧基甲基)丙二酸二乙酯合成路线 （共 6 条）
参考文献
Journal of Organic Chemistry, , vol. 39, # 17 p. 2615 - 2617
反应条件
in diphenylether T=210°C; 15 h;
参考文献
Hsu, Shu-Lin; Chen, Yeh-Long; Tzeng, Cherng-Chyi
Heterocycles, 2004 , vol. 63, # 3 p. 529 - 537
反应条件
sodium tetrahydroborate; ruthenium trichloride in tetrahydrofuran; water
T=20°C; 5 h;
参考文献
Sharma, Pawan K.; Kumar, Surender; Kumar, Pawan; Nielsen, Poul
Tetrahedron Letters, 2007 , vol. 48, # 49 p. 8704 - 8708
反应条件
acetic anhydride; orthoformic acid triethyl ester; aluminium trichloride
参考文献
Dynamit Nobel Aktiengesellschaft
Patent: US4058553 A1, 1977 ;
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
T=0 - 20°C; 2 h; Title compound not separated from byproducts;
参考文献
Reding, Matthew T.; Kaburagi, Yosuke; Tokuyama, Hidetoshi; Fukuyama, Tohru
Heterocycles, 2002 , vol. 56, # 1-2 p. 313 - 330
反应条件
sodium hydride
1.) ether, RT, 3 h, 2.) ether, 0 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Childs, Ronald F.; Kang, Guogong J.; Wark, Teresa A.; Frampton, Christopher S.
Canadian Journal of Chemistry, 1994 , vol. 72, # 10 p. 2084 - 2093
