[2S-(2alpha,5alpha,6beta)]-3,3-二甲基-7-氧代-6-(苯基乙酰氨基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸 4-氧化物合成路线 （共 2 条）
反应条件
1: With N,N'-bis-(trimethylsilyl)-urea in toluene T=60 - 70°C; 1 h; Large scale; 2: With pyridin-2-yl hydrobromide in toluene T=70 - 80°C; Large scale; Concentration;
参考文献
Salehpour, Pooneh; Yegani, Reza; Hajmohammadi, Reza
Organic Process Research and Development, 2012 , vol. 16, # 9 p. 1507 - 1512
反应条件
1: 65 percent / Et3N / dimethylformamide / 24 h / 23 °C 2: 15 percent / H2O; acetonitrile / 23 °C / penicillin acylase; pH=7.3 View Scheme
参考文献
Baldaro; Faiardi; Fuganti; Grasselli; Lazzarini
Tetrahedron Letters, 1988 , vol. 29, # 36 p. 4623 - 4624
