2-氨基-6-[2-(环丙基甲氧基)-6-[(4-甲氧基苯基)甲氧基]苯基]-4-[1-[(1,1-二甲基乙氧基)羰基]-3-哌啶]-3-吡啶羧酸-1,1-二甲基乙酯合成路线 (共 1 条)
反应条件
1: With ammonium acetate in 1,4-dioxane
T=90°C;
2: With chloranil in 1,4-dioxane; ethyl acetate
T=20°C; 1.5 h;
3: With ascorbic acid powder in 1,4-dioxane; ethyl acetate
T=20°C; 1.5 h;
参考文献
BAYER AKTIENGESELLSCHAFT
Patent: WO2003/76447 A1, 2003 ;
Location in patent: Page/Page column 28 ;