(2-氧代-4-苯基丁基)膦酸二乙酯合成路线 （共 6 条）
反应条件
tin(ll) chloride in dichloromethane
2.5 h; Ambient temperature;
参考文献
Holmquist, Christopher R.; Roskamp, Eric J.
Tetrahedron Letters, 1992 , vol. 33, # 9 p. 1131 - 1134
反应条件
magnesium in tetrahydrofuran
T=20°C;
参考文献
Orsini, Fulvia; Di Teodoro, Emanuela; Ferrari, Marinella
Synthesis, 2002 , # 12 p. 1683 - 1688
反应条件
1: sodium iodide / methanol / 24 h / Ambient temperature
2: Ambient temperature
View Scheme
参考文献
Ryglowski, Artur; Kafarski, Pawel
Tetrahedron, 1996 , vol. 52, # 32 p. 10685 - 10692
反应条件
1: 2.) HCl / 1.) dietyl ether, RT, 1 h, 2.) diethyl ether
2: sodium iodide / methanol / 24 h / Ambient temperature
3: Ambient temperature
View Scheme
参考文献
Ryglowski, Artur; Kafarski, Pawel
Tetrahedron, 1996 , vol. 52, # 32 p. 10685 - 10692
反应条件
(i) nBuNH2, (ii) aq. oxalic acid, Et2O; Multistep reaction;
参考文献
Chattha,M.S.; Aguiar,A.M.
Journal of Organic Chemistry, 1973 , vol. 38, # 16 p. 2908 - 2909
反应条件
Ambient temperature; Yield given;
参考文献
Ryglowski, Artur; Kafarski, Pawel
Tetrahedron, 1996 , vol. 52, # 32 p. 10685 - 10692
