1-(4-甲基噻唑-2-基)-哌嗪合成路线 （共 3 条）
反应条件
triethylamine in tetrahydrofuran
T=160°C; 2 h; Microwave irradiation;
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: WO2006/72436 A1, 2006 ;
Location in patent: Page/Page column 34 ;
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 3 h;
参考文献
Kondo, Takashi; Nekado, Takahiro; Sugimoto, Isamu; Ochi, Kenya; Takai, Shigeyuki; Kinoshita, Atsushi; Hatayama, Akira; Yamamoto, Susumu; Kishikawa, Katsuya; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 4 p. 1613 - 1631
参考文献
Gruenenthal GmbH
Patent: US2007/112011 A1, 2007 ;
