4,4'-双甲氧基三苯甲基氯合成路线 （共 132 条）
反应条件
thionyl chloride in n-heptane 1.) 0 deg C, 10 min, 2.) RT, 10 min, 3.) reflux, 1 h;
参考文献
Huszthy; Bradshaw; Krakowiak; Wang; Dalley
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1197 - 1207
反应条件
1: 72 percent / Grignard reaction 2: 82 percent / SOCl2 / diethyl ether / Heating View Scheme
参考文献
Izso, Gyoengyi; Huszthy, Peter; Lempert, Karoly; Fetter, Jozsef; Simig, Gyula; et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 769 - 778
反应条件
1: 72 percent / Grignard reaction 2: 82 percent / SOCl2 / diethyl ether / Heating View Scheme
参考文献
Izso, Gyoengyi; Huszthy, Peter; Lempert, Karoly; Fetter, Jozsef; Simig, Gyula; et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1989 , p. 769 - 778
反应条件
perchloric acid; water; sodium chloride in methanol T=25°C; other temperatures; Equilibrium constant;
参考文献
Lee, Won Heui; Maskill, H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 7 p. 1463 - 1466
反应条件
1: 1.) AlCl3, 2.) aq. H2SO4 / 1.) 2 h 2: AcCl / 1.5 h / Heating View Scheme
参考文献
Rathore, M.; Rani, P.; Mathur, N. K.; Narang, C. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 7 p. 634 - 635
反应条件
1: 1.) AlCl3, 2.) aq. H2SO4 / 1.) 2 h 2: AcCl / 1.5 h / Heating View Scheme
参考文献
Rathore, M.; Rani, P.; Mathur, N. K.; Narang, C. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 7 p. 634 - 635
反应条件
N-ethyl-N,N-diisopropylamine in pyridine 3 h; Ambient temperature;
参考文献
Seela, Frank; Muth, Heinz-Peter
Liebigs Annalen der Chemie, 1988 , p. 215 - 220
参考文献
Novopashina; Sinyakov; Ryabinin; Perrouault; Giovannangeli; Venyaminova; Boutorine
Russian Journal of Bioorganic Chemistry, 2013 , vol. 39, # 2 p. 138 - 152
Bioorg. Khim., 2013 , vol. 39, # 2 p. 159 - 174,16
反应条件
1: 76 percent / pyridine 2: 83 percent / tetrazole, diisopropylamine / CH2Cl2 View Scheme
参考文献
Sudhakar Rao; Jayaraman; Durland; Revankar
Tetrahedron Letters, 1992 , vol. 33, # 50 p. 7651 - 7654
反应条件
pyridine T=20°C; 2 h;
参考文献
Yamada, Kenji; Hattori, Yusaku; Inde, Takeshi; Kanamori, Takashi; Ohkubo, Akihiro; Seio, Kohji; Sekine, Mitsuo
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 3 p. 776 - 778
