4,4'-双甲氧基三苯甲基氯合成路线 （共 132 条）
反应条件
N-ethyl-N,N-diisopropylamine; 4-(N,N-dimethlyamino)pyridine in pyridine
4 h; Ambient temperature;
参考文献
Meier; Neumann; Andre; Henin; Huynh-Dinh
Journal of Organic Chemistry, 1992 , vol. 57, # 26 p. 7300 - 7308
反应条件
1: 4,4'-dimethoxytriphenylmethyl chloride; 3'-Deoxyadenosine With pyridine; N-ethyl-N,N-diisopropylamine in 1,4-dioxane
T=20°C; 3 h;
2: benzoyl chloride in pyridine
参考文献
Charubala, Ramamurthy; Pfleidere, Wolfgang; Suhadolnik, Robert J.; Iacono, Kathryn T.; Muto, Nicholas F.; Homan, Joseph W.; Martinand-Mari, Camille; Horvath, Susan E.; Henderson, Earl E.; Steele, Amber; Rogers, Thomas J.
Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2284 - 2299
参考文献
Kumar, Anil; Dass, Debasis; Atreyi; Rao; Katti
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 10-11 p. 1783 - 1796
反应条件
N-ethyl-N,N-diisopropylamine in pyridine
3 h; Ambient temperature;
参考文献
Seela; Kehne
Tetrahedron, 1985 , vol. 41, # 22 p. 5387 - 5392
反应条件
1: NEt3 / tetrahydrofuran
2: NEt3; CuI / Pd(PPh3)4 / acetone
View Scheme
参考文献
Berry, David A.; Jung, Kee-Yong; Wise, Dean S.; Sercel, Anthony D.; Pearson, William H.; Mackie, Hugh; Randolph, John B.; Somers, Robert L.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2457 - 2461
反应条件
1: 92 percent / pyridine / 19 h / 20 °C
2: 73 percent / NEt3; CuI / Pd(PPh3)4 / acetone / 40 h / 20 °C
View Scheme
参考文献
Berry, David A.; Jung, Kee-Yong; Wise, Dean S.; Sercel, Anthony D.; Pearson, William H.; Mackie, Hugh; Randolph, John B.; Somers, Robert L.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2457 - 2461
反应条件
1: NEt3 / tetrahydrofuran
2: NEt3; CuI / Pd(PPh3)4 / acetone
3: NEt3; CuI / methanol
4: 49 percent / NH3 / methanol; tetrahydrofuran / 22 h / 50 °C
View Scheme
参考文献
Berry, David A.; Jung, Kee-Yong; Wise, Dean S.; Sercel, Anthony D.; Pearson, William H.; Mackie, Hugh; Randolph, John B.; Somers, Robert L.
Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2457 - 2461
反应条件
in dichloromethane
T=20°C; 20 h;
参考文献
Viirre; Hudson
Organic letters, 2001 , vol. 3, # 24 p. 3931 - 3934
反应条件
sodium hydroxide in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Bleasdale, Christine; Ellwood, Simon B.; Golding, Bernard T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 803 - 805
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine
参考文献
Kim, Su Jeong; Bang, Eun-Kyoung; Kim, Byeang Hyean
Synlett, 2003 , # 12 p. 1838 - 1840
