4,4'-双甲氧基三苯甲基氯合成路线 （共 132 条）
反应条件
1: in pyridine T=20°C; 6 h; 2: With sodium hydrogencarbonate in water; ethyl acetate 2 h;
参考文献
Mitsui Chemicals, Inc.
Patent: US2003/229223 A1, 2003 ;
Location in patent: Page 4 ;
反应条件
2: 29percent aq. ammonia, 4-dimethylaminopyridine / pyridine; triethylamine / 0.5 h View Scheme
参考文献
Ti, G. S.; Gaffney, B. L.; Jones, R. A.
Journal of the American Chemical Society, 1982 , vol. 104, # 5 p. 1316 - 1319
反应条件
1: benzoic acid anhydride; [14C]-Deoxycytidine in pyridine T=90°C; 1 h; 2: 4,4'-dimethoxytriphenylmethyl chloride in pyridine T=20°C; 10 h; Further stages.;
参考文献
Radi, Marco; Spinosa, Raffaella; Parlato, Maria Cristina; Corelli, Federico; Botta, Maurizio
Heterocycles, 2006 , vol. 69, # 1 p. 151 - 166
反应条件
4-(N,N-dimethlyamino)pyridine in 1,4-dioxane; pyridine 2 h;
参考文献
McGee, Danny P. C.; Martin, John C.; Webb, Austin S.
Synthesis, 1983 , # 7 p. 540 - 541
反应条件
1: 91 percent / pyridine / 3 h / 20 °C 2: lithium triethylborohydride / tetrahydrofuran / 16 h / cooling View Scheme
参考文献
Timoshchuk, Victor A.; Hogrefe, Richard I.; Vaghefi, Morteza M.
Nucleosides, Nucleotides and Nucleic Acids, 2004 , vol. 23, # 1-2 p. 171 - 181
反应条件
pyridine T=20°C; 3 h;
参考文献
EP1253154 A1, ;
Example 1 ;
参考文献
Tetrahedron Letters, , vol. 33, # 48 p. 7319 - 7323
反应条件
1: 77 percent / pyridine, triethylamine, 4-dimethylaminopyridine / 4 h 2: pyridine, triethylamine, 4-dimethylaminopyridine / 0.5 h 3: pyridine, triethylamine, 4-dimethylaminopyridine / 2 h / Ambient temperature 4: 29percent aq. ammonia, 4-dimethylaminopyridine / pyridine; triethylamine / 0.5 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 104, # 5 p. 1316 - 1319
反应条件
pyridine T=20°C; 2.5 h;
参考文献
EP1253154 A1, ;
Example 2 ;
参考文献
Vu, Huynh; McCollum, Christie; Jacobson, Karen; Theisen, Pete; Vinayak, Ravi; et al.
Tetrahedron Letters, 1990 , vol. 31, # 50 p. 7269 - 7272
