4,4'-双甲氧基三苯甲基氯合成路线 （共 132 条）
反应条件
1: 85 percent / pyridine / 20 °C 2: 80 percent / 1H-tetrazole / acetonitrile / 2 h / 20 °C View Scheme
参考文献
Kumar, Anil; Dass, Debasis; Atreyi; Rao; Katti
Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 10-11 p. 1783 - 1796
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=20°C; 16 h;
参考文献
Fiammengo, Roberto; Musilek, Kamil; Jaeschke, Andres
Journal of the American Chemical Society, 2005 , vol. 127, # 25 p. 9271 - 9276
反应条件
pyridine T=20°C; 12 h;
参考文献
Sando, Shinsuke; Abe, Kenji; Sato, Nobuhiko; Shibata, Toshihiro; Mizusawa, Keigo; Aoyama, Yasuhiro
Journal of the American Chemical Society, 2007 , vol. 129, # 19 p. 6180 - 6186
反应条件
pyridine in methanol
参考文献
ISIS Pharmaceuticals, Inc.
Patent: US5914396 A1, 1999 ;
反应条件
pyridine 0.75 h; Inert atmosphere;
参考文献
Barbeyron, Renaud; Wengel, Jesper; Vasseur, Jean-Jacques; Smietana, Michael
Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 495 - 500
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine; triethylamine / 4 h / 20 °C 2: pyridine / dichloromethane / 0.08 h / 20 °C / Large scale reaction View Scheme
参考文献
Janczyk, Matthaeus; Appel, Bettina; Springstubbe, Danilo; Fritz, Hans-Joachim; Mueller, Sabine
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 8 p. 1510 - 1513
反应条件
pyridine T=20°C; 2 h;
参考文献
Webb; Mitsuya; Broder
Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1475 - 1479
反应条件
triethylamine in pyridine 1.5 h;
参考文献
Helvetica Chimica Acta, , vol. 80, # 6 p. 1952 - 1971
反应条件
triethylamine in pyridine; water; ethyl acetate
参考文献
US2013/267697 A1, ;
Page/Page column ;
反应条件
1: 65 percent / pyridine / 20 h / 5 °C 2: 50 percent 3: 65 percent / diisopropylethylamine / tetrahydrofuran View Scheme
参考文献
Chaix, Carole; Molko, Didier; Teoule, Robert
Tetrahedron Letters, 1989 , vol. 30, # 1 p. 71 - 74
