4,5'-二甲基异补骨脂素合成路线 （共 19 条）
反应条件
in various solvent(s)
0.3 h; Irradiation;
参考文献
Saidi, Mohammad R.; Bigdeli, Kamal
Journal of Chemical Research - Part S, 1998 , # 12 p. 800 - 801
反应条件
1: 60 percent / N-bromosuccinimide, dibenzoylperoxide / CCl4 / 10 h / Heating
2: benzene / 8 h / Heating
3: 75 percent / Et3N / toluene / 16 h / Heating
View Scheme
参考文献
Soman, Shubhangi S.; Trivedi, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 8 p. 532 - 534
反应条件
1: benzene / 8 h / Heating
2: 75 percent / Et3N / toluene / 16 h / Heating
View Scheme
参考文献
Soman, Shubhangi S.; Trivedi, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 8 p. 532 - 534
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene
12 h; Heatingother 6- or 8-allyl-7-hydroxycoumarins, DDQ oxidation;
参考文献
Prashant, Avula; Krupadanam, Gazula Levi David; Srimannarayana, Gutely
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 4 p. 1191 - 1193
反应条件
in dichloromethane
72 h; Heating;
参考文献
Nicolaides, Demetrios N.; Bezergiannidou-Balouctsi, Catherine; Litinas, Konstantinos E.; Malamidou-Xenikaki, Elizabeth; Mentzafos, Demetrios; Terzis, Aris
Journal of Chemical Research, Miniprint, 1993 , # 3 p. 826 - 852
反应条件
sulfuric acid; nitric acid
4 h; Ambient temperature;
参考文献
Valenti; Montanari; Scapini; Giusti; Cima
Archiv der Pharmazie, 1980 , vol. 313, # 5 p. 449 - 453
反应条件
1: 51 percent / conc. H2SO4, HNO3 / 4 h / Ambient temperature
2: 62 percent / H2 / 5 percent Pd/C / tetrahydrofuran
3: 67 percent / K2CO3 / acetone / 1 h / Heating
4: 80 percent / benzene / 2 h / Heating
View Scheme
参考文献
Valenti; Montanari; Scapini; Giusti; Cima
Archiv der Pharmazie, 1980 , vol. 313, # 5 p. 449 - 453
参考文献
Consiglio Nazionale delle Ricerche
Patent: US4312883 A1, 1982 ;
反应条件
1: 63 percent / acetic acid / 48 h / Ambient temperature
2: 62 percent / H2O
View Scheme
参考文献
Dall'Acqua; Vedaldi; Caffieri; Guiotto; Rodighiero; Baccichetti; Carlassare; Bordin
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 178 - 184
