(S,S)-(-)-双(α-甲苄基)胺盐酸盐合成路线 （共 16 条）
反应条件
lead(IV) acetate in benzene T=50 - 60°C; 5 h;
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
反应条件
N-[(R)-1-(1-naphthyl)ethyl]carbamoyl-derivatized cyclofructan-6 column in ethanol; n-heptane; trifluoroacetic acid T=20°C; Resolution of racemate;
参考文献
Sun, Ping; Wang, Chunlei; Breitbach, Zachary S.; Zhang, Ying; Armstrong, Daniel W.
Analytical Chemistry, 2009 , vol. 81, # 24 p. 10215 - 10226
反应条件
chiral stationary phase including (R)-naphthylethyl-carbamate-functionalized CF6 in ethanol; n-heptane; trifluoroacetic acid T=20°C; Purification / work up;
参考文献
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; ARMSTRONG, Daniel, W.; PING, Sun; BREITBACH, Zachary, S.; WANG, Chunlei
Patent: WO2010/148191 A2, 2010 ;
Location in patent: Page/Page column 45-49; 54 ;
反应条件
1: toluene / Heating 2: NaBH4 View Scheme
参考文献
Clayden, Jonathan; Knowles, Faye E.; Menet, Christel J.
Tetrahedron Letters, 2003 , vol. 44, # 16 p. 3397 - 3400
反应条件
1: toluene / Heating 2: NaBH4 View Scheme
参考文献
Clayden, Jonathan; Knowles, Faye E.; Menet, Christel J.
Tetrahedron Letters, 2003 , vol. 44, # 16 p. 3397 - 3400
反应条件
1: 77 percent / 9 h 2: 87 percent / diethyl ether / 10 h 3: 48.5 percent / lead tetracetate / benzene / 5 h / 50 - 60 °C View Scheme
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
反应条件
1: 77 percent / 9 h 2: 87 percent / diethyl ether / 10 h 3: 48.5 percent / lead tetracetate / benzene / 5 h / 50 - 60 °C View Scheme
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
反应条件
1: 85 percent / 5 h / Heating 3: 51 percent / lead tetracetate / benzene View Scheme
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
反应条件
2: 51 percent / lead tetracetate / benzene View Scheme
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
反应条件
1: 87 percent / diethyl ether / 10 h 2: 48.5 percent / lead tetracetate / benzene / 5 h / 50 - 60 °C View Scheme
参考文献
Alcaide, Benito; Lopez-Mardomingo, Carmen; Perez-Ossorio, Rafael; Plumet, Joaquin
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 45 - 48
