N-(4-叔丁基-2-硝基苯基)乙酰胺合成路线 （共 12 条）
反应条件
1.1: AlCl3, aluminium chloride / 1,2-dichloro-ethane / 1 h / -12 - 5 °C / |Large scale
2.1: acetic acid; acetic anhydride / 0.42 h / 20 °C / |Large scale
2.2: 2 h / 20 - 25 °C / |Large scale
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参考文献
PFIZER INC.; BAGAL, Sharanjeet Kaur; BROWN, Alan Daniel; KEMP, Mark Ian; KLUTE, Wolfgang; MARRON, Brian Edward; MILLER, Duncan Charles; SKERRATT, Sarah Elizabeth; SUTO, Mark J.; WEST, Christopher William; MALET SANZ, Laia
Patent: WO2013/114250 A1, 2013 ;
反应条件
1: Raney nickel; ethanol / 50 °C / Hydrogenation
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参考文献
Biekart et al.
Recueil des Travaux Chimiques des Pays-Bas, 1952 , vol. 71, p. 321,338
